Quoting%20commentary for Orlah 2:6

וּלְמָה אָמְרוּ כָּל הַמְחַמֵּץ וְהַמְתַבֵּל וְהַמְדַמֵּעַ לְהַחֲמִיר, מִין בְּמִינוֹ. לְהָקֵל וּלְהַחֲמִיר, מִין בְּשֶׁאֵינוֹ מִינוֹ. כֵּיצַד, שְׂאֹר שֶׁל חִטִּים שֶׁנָּפַל לְתוֹךְ עִסַּת חִטִּים, וְיֵשׁ בּוֹ כְדֵי לְחַמֵּץ, בֵּין שֶׁיֵּשׁ בּוֹ לַעֲלוֹת בְּאֶחָד וּמֵאָה וּבֵין שֶׁאֵין בּוֹ לַעֲלוֹת בְּאֶחָד וּמֵאָה, אָסוּר. אֵין בּוֹ לַעֲלוֹת בְּמֵאָה וְאֶחָד, בֵּין שֶׁיֵּשׁ בּוֹ כְדֵי לְחַמֵּץ, בֵּין שֶׁאֵין בּוֹ כְדֵי לְחַמֵּץ, אָסוּר:

And concerning what they said, All that cause fermentation, or season, or make a mixture <i>Meduma</i> when is [the rule applied] stringently? [In the case of] a species [mixed] with its [like] species. [When is the rule applied sometimes] leniently and [sometimes] stringently? [In the case of] a species [mixed] with a different kind of species. How so? If leaven of wheat fell into wheat dough and there is enough to cause leavening, whether there is enough to neutralize in one hundred and one, or there is not enough to neutralize in one hundred and one, it is prohibited. If there is not enough to neutralize in one hundred and one, whether there is enough to cause leavening or there is not enough to cause leavening, it is prohibited.

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